BG Biogeosciences BG Biogeosciences 1726-4189 Copernicus Publications Göttingen, Germany 10.5194/bg-7-585-2010 Dynamics and distribution of natural and human-caused hypoxia Rabalais N. N. 1 Díaz R. J. 2 Levin L. A. 3 Turner R. E. 4 Gilbert D. 5 Zhang J. 6 Louisiana Universities Marine Consortium, Chauvin, Louisiana 70344, USA Virginia Institute of Marine Science, College of William and Mary, Gloucester Point, Virginia 23062, USA Integrative Oceanography Division, Scripps Institution of Oceanography, 9500 Gilman Drive, La Jolla, California 92093-0218, USA Department of Oceanography and Coastal Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, USA Institut Maurice-Lamontagne, Pêches et Océans Canada, 850 route de la mer, Mont-Joli, Québec, G5H 3Z4, Canada State Key Laboratory of Estuarine and Coastal Research, East China Normal University, 3663 Zhongshan Road North, Shanghai 200062, China 12 02 2010 7 2 585 619 Copyright: © 2010 N. N. Rabalais et al. 2010 This work is licensed under the Creative Commons Attribution 3.0 Unported License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/3.0/ This article is available from https://bg.copernicus.org/articles/7/585/2010/bg-7-585-2010.html The full text article is available as a PDF file from https://bg.copernicus.org/articles/7/585/2010/bg-7-585-2010.pdf

Water masses can become undersaturated with oxygen when natural processes alone or in combination with anthropogenic processes produce enough organic carbon that is aerobically decomposed faster than the rate of oxygen re-aeration. The dominant natural processes usually involved are photosynthetic carbon production and microbial respiration. The re-supply rate is indirectly related to its isolation from the surface layer. Hypoxic water masses (&lt;2 mg L<sup>&minus;1</sup>, or approximately 30% saturation) can form, therefore, under "natural" conditions, and are more likely to occur in marine systems when the water residence time is extended, water exchange and ventilation are minimal, stratification occurs, and where carbon production and export to the bottom layer are relatively high. Hypoxia has occurred through geological time and naturally occurs in oxygen minimum zones, deep basins, eastern boundary upwelling systems, and fjords. <br><br> Hypoxia development and continuation in many areas of the world's coastal ocean is accelerated by human activities, especially where nutrient loading increased in the Anthropocene. This higher loading set in motion a cascading set of events related to eutrophication. The formation of hypoxic areas has been exacerbated by any combination of interactions that increase primary production and accumulation of organic carbon leading to increased respiratory demand for oxygen below a seasonal or permanent pycnocline. Nutrient loading is likely to increase further as population growth and resource intensification rises, especially with increased dependency on crops using fertilizers, burning of fossil fuels, urbanization, and waste water generation. It is likely that the occurrence and persistence of hypoxia will be even more widespread and have more impacts than presently observed. <br><br> Global climate change will further complicate the causative factors in both natural and human-caused hypoxia. The likelihood of strengthened stratification alone, from increased surface water temperature as the global climate warms, is sufficient to worsen hypoxia where it currently exists and facilitate its formation in additional waters. Increased precipitation that increases freshwater discharge and flux of nutrients will result in increased primary production in the receiving waters up to a point. The interplay of increased nutrients and stratification where they occur will aggravate and accelerate hypoxia. Changes in wind fields may expand oxygen minimum zones onto more continental shelf areas. On the other hand, not all regions will experience increased precipitation, some oceanic water temperatures may decrease as currents shift, and frequency and severity of tropical storms may increase and temporarily disrupt hypoxia more often. <br><br> The consequences of global warming and climate change are effectively uncontrollable at least in the near term. On the other hand, the consequences of eutrophication-induced hypoxia can be reversed if long-term, broad-scale, and persistent efforts to reduce substantial nutrient loads are developed and implemented. In the face of globally expanding hypoxia, there is a need for water and resource managers to act now to reduce nutrient loads to maintain, at least, the current status.

 References Alexander, R. B., Smith, R. A., and Schwarz, G. E.: Differences in phosphorus and nitrogen delivery to the Gulf of Mexico from the Mississippi River basin, Environ. Sci. Technol., 42, 822–830, 2008. Andrews, M. J. and Rickard, D. G.: Rehabilitation of the inner Thames estuary, Mar. Pollut. Bull., 11, 327–332, 1980. Arntz, W. E., Gallardo, V. A., Gutiérrez, D., Isla, E., Levin, L. A., Mendo, J., Neira, C., Rowe, G. T., Tarazona, J., and Wolff, M.: El Niño and similar perturbation effects on the benthos of the Humboldt, California, and Benguela Current upwelling ecosystems, Adv. Geosci., 6, 243–265, 2006. Arrigo, K. R.: Marine manipulations, Nature, 450, 491–492, 2007. Baden, S. P., Loo, L.-O., Pihl, L., and Rosenberg, R.: Effects of eutrophication on benthic communities including fish Swedish west coast, Ambio, 19, 113–122, 1990a. Baden, S. P., Pihl, L., and Rosenberg, R.: Effects of oxygen depletion on the ecology, blood physiology and fishery of the Norway lobster <i>Nephrops norvegicus</i>, Mar. Ecol. Prog. Ser., 67, 141–155, 1990b. Baird, D., Christian, R. R., Peterson, C. H., and Johnson, G. A.: Consequences of hypoxia on estuarine ecosystem function Energy diversion from consumers to microbes, Ecol. Appl., 14, 805–822, 2004. Bakan, G. and Buyukgungor, H.: The Black Sea, Mar. Pollut. Bull., 41, 24–43, 2000. Bakun, A.: Global climate change and intensification of coastal ocean upwelling, Science, 247, 198–201, 1990. Bakun, A. and Weeks, S. J.: Greenhouse gas buildup, sardines, submarine eruptions, and the possibility of abrupt degradation of intense marine upwelling ecosystems, Ecol. Lett., 7, 1015–1023, 2004. Banse, K.: On upwelling and bottom trawling off the Southwest coast off India, J. Mar. Biol. Assoc. India, 1, 33–49, 1959. Banse, K.: Hydrograghy of the Arabian Sea shelf of India and Pakistan and effects on demersal fishes, Deep-Sea Res. I, 15, 45–79, 1968. Barmawidjaja, D. M., van der Zwaan, G. J., Jorissen, F. J., and Puskaric, S.: 150 years of eutrophication in the northern Adriatic Sea Evidence from a benthic foraminiferal record, Mar. Geol., 122, 367–384, 1995. Barth, J. A., Menge, B. A., Lubchenco, J., Chan, F., Bane, J. M., Kirincich, A. R., McManus, M. A., Nielsen, K. J., Pierce, S. D., and Washburn, L.: Delayed upwelling alters nearshore coastal ocean ecosystems in the northern California current, P. Natl. Acad. Sci. USA, 104, 3719–3724, 2007. Batiuk, R. A., Breitburg, D. L., Diaz, R. J., Cronin, T. M., Secor, D. H., and Thursby, G.: Derivation of habitat-specific dissolved oxygen criteria for Chesapeake Bay and its tidal tributaries, J. Exp. Mar. Biol. Ecol., 238, S204–S215, 2009. Baustian, M. M. and Rabalais, N. N.: Seasonal composition of benthic macroinfauna exposed to hypoxia in the northern Gulf of Mexico, Estuar. Coasts, 32, 975–983, 2009. Bender, M. A., Knutson, T. R., Tuleya, R. E., Sirutis, J. J., Vecchi, G. A., Barner,S. T., and Held, I. M.: Modeled impact of anthropogenic warning on the frequency of intense Atlantic hurricanes, Science, 327, 454–458, 2010. Bennett, E. M., Carpenter, S. R., and Caraco, N. F.: Human impact on erodable phosphorus and eutrophication A global perspective, BioScience, 51, 227–234, 2001. Benović, A., Justić, D., and Bender, A.: Enigmatic changes in the hydromedusan fauna of the northern Adriatic Sea, Nature, 326, 597–600, 1987. Berelson, W. M.: The flushing of two deep-sea basins, Southern California Borderland, Limnol. Oceanogr., 36, 1150–1166, 1991. Berezina, N. A.: Spatial distribution of macrofauna in a littoral zone with drifting macroalgae in the Neva estuary, Estonian J. Ecol., 57, 198–213, 2008. Boesch, D. F.: Challenges and opportunities for science in reducing nutrient over-enrichment of coastal ecosystems, Estuaries, 25, 744–758, 2002. Boesch, D.F.: Scientific requirements for ecosystem-based management in the restoration of Chesapeake Bay and coastal Louisiana, Ecol. Eng., 26, 6–26, 2006. Boesch, D. F. and Rabalais, N. N.: Effects of hypoxia on continental shelf benthos Comparisons between the New York Bight and the Northern Gulf of Mexico, in: Modern and Ancient Continental Shelf Anoxia, edited by: Tyson, R. V. and Pearson, T. H., Geol. Soc. Spec. Publ. 58, The Geological Society, London, 27–34, 1991. Bograd, S. J., Castro, C. G., Di Lorenzo, E., Palacios, D. M., Bailey, H. R., and Gilly, W.: The shoaling of the hypoxic boundary in the California Current, Geophys. Res. Let., 35, L12607, https://doi.org/10.1029/2008GL034185, 2008. Bopp, L., LeQuéré, C., Heimann, M., Manning, A. C., and Monfray, P.: Climate-induced oceanic oxygen fluxes Implications for the contemporary carbon budget, Global Biogeochem. Cy., 16, 1022, https://doi.org/10.10292001GB001445, 2002. Boynton, W. R., Garber, J. H., Summers, R., and Kemp, W. M.: Inputs, transformations, and transport of nitrogen and phosphorus in Chesapeake Bay and selected tributaries, Estuaries, 18, 285–314, 1995. Brand, T. D. and Griffiths, C.: Seasonality in the hydrography and biogeochemistry across the Pakistan margin of the NE Arabian Sea, Deep-Sea Res. II, 56, 283–295, 2009. Brandt, S. B. and Kirsch, J. A. Y.: Spatially explicit models of striped bass growth potential in Chesapeake Bay, Trans. Am. Fish. Soc., 122, 845–869, 1993. Brearley, A.: Ernest Hodgkin's Swanland Estuaries and Coastal Lagoons of South-western Australia, University of Western Australia Press, Crawley, Australia, 550&nbsp;pp., 2005. Breitburg, D. L.: Episodic hypoxia in Chesapeake Bay Interacting effects of recruitment, behavior, and physical disturbance, Ecol. Monogr., 62, 525–546, 1992. Breitburg, D. L., Hondorp, D. W., Davias, L. W., and Diaz, R. J.: Hypoxia, nitrogen and fisheries Integrating effects across local and global landscapes, Ann. Rev. Mar. Sci., 1, 329–350, 2009. Brewer, P. G. and Peltzer, E. T.: Limits to marine life, Science, 324, 347–348, 2009. Bricker, S., Longstaff, B., Dennison, W., Jones, A., Boicourt, K., Wicks, C., and Woerner, J.: Effects of nutrient enrichment in the Nation's estuaries A decade of change. NOAA Coastal Ocean Program Decision Analysis Series No.&nbsp;26, National Centers for Coastal Ocean Science, Silver Spring, Maryland, 328&nbsp;pp., 2007. Brill, R. W.: Selective advantages conferred by the high performance physiology of tunas, billfishes, and dolphin fish, Comp. Biochem. Physiol., 113, 3–15, 1996. Brongersma-Sanders, M.: Mass mortality in the sea, in: Hedgpeth, J. W. (ed.), Treatise on Marine Ecology and Paleoecology, Vol. 1, Waverly Press, Baltimore, Maryland, 941–1010, 1957. Brown, C. A., Nelson, W. G., Boese, B. L., DeWitt, T. H., Eldridge, P. M., Kaldy, J. E., Lee II, H., Power, J. H., and Young, D. R.: An approach to developing nutrient criteria for Pacific northwest estuaries A case study of Yaquina Estuary, EPA/600/R-07/046, Oregon, U.S. Environmental Protection Agency, Washington, DC, 183&nbsp;pp., 2007. Brush, G. S.: Stratigraphic evidence of eutrophication in an estuary, Water Resour. Res., 20, 531–541, 1984. Brush, G. S.: Historical land use, nitrogen, and coastal eutrophication A paleoecological perspective, Estuar. Coasts, 32, 18–28, 2009. Caddy, J. F.: Towards a comparative evaluation of human impacts on fishery ecosystems of enclosed and semi-enclosed seas, Rev. Fish. Sci., 1, 57–95, 1993. Chabot, D. and Dutil, J.-D.: Reduced growth of Atlantic cod in non-lethal hypoxic conditions, J. Fish Biol., 55, 472–491, 1999. Chapman, P. and Shannon, L. V.: The Benguela ecosystem Part II Chemistry and related processes, Oceanogr. Mar. Biol. Ann. Rev., 23, 183–251, 1985. Chan, F., Barth, J., Lubchenco, J., Kirincich, J., Weeks, A., Peterson, H., Mengl, W. T., and Chan, B. A.: Emergence of anoxia in the California Current Large Marine Ecosystem, Science, 319, p.&nbsp;920, 2008. Chavez, F. P., Ryan, J., Lluch-Cota, S. E., and \&nbsp;{N}iquen, C. M.: From anchovies to sardines and back Multidecadal change in the Pacific Ocean, Science, 299, 217–221, 2003. Cheek, T. E., Van Den Avyle, M. J., and Coutant, C. C.: Influence of water quality on distribution of striped bass in a Tennessee River impoundment, Trans. Am. Fish. Soc., 114, 67–76, 1985. Chen, C.-C., Gong, G.-C., and Shiah, F.-K.: Hypoxia in the East China Sea One of the largest coastal low-oxygen areas in the world, Mar. Environ. Res., 64, 399–408, 2007. Chen, G. H., Leong, I. M., Liu, J., Huang, J. C., Lo, I. M. C., and Yen, B. C.: Oxygen deficit determinations for a major river in eastern Hong Kong, China, Chemosphere, 41, 7–13, 2000. Chen, T. A. C. and Wang, S. L.: Carbon, alkalinity and nutrient budgets on the East China Sea continental shelf, J. Geophy. Res., 104, 20675–20686, 1999. Cheng W., Liu, C.-H., Hsu, J.-P., and Chen, J.-C.: Effect of hypoxia on the immune response of giant freshwater prawn <i>Macrobrachium rosenbergii</i> and its susceptibility to pathogen <i>Enterococcus</i>, Fish Shellfish Immunol., 13, 351–365, 2002. Cheung, W. W. L., Lam, V. W. Y., Sarmiento, J. L., Kearney, K., Watson, R., Zeller, D., and Pauly, D.: Large-scale redistribution of maximum fisheries catch potential in the global ocean under climate change, Glob. Change Biol., 16, 24–35, 2010. Childress, J. J. and Seibel, B. A.: Life at stable low oxygen levels Adaptations of animals to oceanic oxygen minimum layers, J. Exp. Biol., 201, 1223–1232, 1998. Childs, C. R., Rabalais, N. N., Turner, R. E., and Proctor, L. M.: Sediment denitrification in the Gulf of Mexico zone of hypoxia, Mar. Ecol. Prog. Ser., 240, 285–290, (Erratum, 247, p.&nbsp;310, 2003), 2002. Christie, N. D. and Moldan, A. G. S.: Effects of fish factory effluents on the benthic macrofauna of Saldanha Bay, Mar. Pollut. Bull., 8, 41–45, 1977. Cloern, J. E.: Review Our evolving conceptual model of the coastal eutrophication problem, Mar. Ecol. Prog. Ser., 210, 223–253, 2001. Cockroft, A. C.: <i>Jasus lalandii</i> "walkouts" or mass strandings in South Africa during the 1990's An overview, Mar. Freshwater Res., 52, 1085–1094, 2001. Committee on Environment and Natural Resources (CENR): Integrated Assessment of Hypoxia in the Northern Gulf of Mexico, National Science and Technology Council, Washington, DC, 2000. Conley, D. J. and Josefson, A. B.: Hypoxia, nutrient management and restoration in Danish waters, in: Coastal Hypoxia Consequences for Living Resources and Ecosystems, edited by: Rabalais, N. N. and Turner, R. E., Coastal and Estuarine Studies 58, Washington, DC, American Geophysical Union, 425–434, 2001. Conley, D. J., Humborg, C., Rahm, L., Savchuk, O. P., and Wulff, F.: Hypoxia in the Baltic Sea and basin-scale changes in phosphorus biogeochemistry, Environ. Sci. Technol., 36, 5315–5320, 2002a. Conley, D. J., Markager, S., Andersen, J., Ellermann, T., and Svendsen, L. M.: Coastal eutrophication and the Danish National Aquatic Monitoring and Assessment Program, Estuaries, 25, 848–861, 2002b. Conley, D. J., Carstensen, J., Ǽrtebjerg, G., Christensen, P. B., Dalsgaard, T., Hansen, J. L. S., and Josefson, A. B.: Long-term changes and impacts of hypoxia in Danish coastal waters, Ecol. Appl., 17, Suppl., S165–S184, 2007. Conley, D. J., Bonsdorff, E., Carstensen, J., Destouni, G., Gustafsson, B. G., Hansson, L.-A., Rabalais, N. N., Voss, M., and Zillén, L.: Tackling hypoxia in the Baltic Sea Is engineering a solution?, Environ. Sci. Technol., 43, 3407–3411, 2009a. Conley, D. J., Björck, S., Bonsdorff, E., Carstensen, J., Destouni, G., Gustafsson, B. G., Hietanen, S., Kortekaas, M., Kuosa, H., Meier, H. E. M., Müller-Karulis, B., Nordberg, K., Norkko, A., Nürrnberg, G., Pitkänen, H., Rabalais, N. N., Rosenberg, R., Savchuk, O., Slump, C. P., Voss, M., Wulff, F., and Zillén, L.: Hypoxia-related processes in the Baltic Sea, Environ. Sci. Technol., 43, 3412–3420, 2009b. Conseil Permanent International pour l'Exploration de la Mer: Bulletin Hydrographique pour l'année 1935, Series B1, Charlottelund Slot, Denmark: Le Bureau du Conseil, Service Hydrographique, 1936. Cooper, S. R. and Brush, G. S.: Long term history of Chesapeake Bay anoxia, Science, 254, 992–996, 1991. Costanza, R., d'Arge, R., de Groot, R. S., Farber, S., Grasso, M., Hannon, B., Limburg, K., Naeem, S., O'Neill, R.V., Paruelo, J., Raskin, R. G., Sutton, P., and van den Belt, M.: The value of the world's ecosystem services and natural capital, Nature, 387, 253–260, 1997. Coutant, C. C. and Benson, D. L.: Summer habitat suitability for striped bass in Chesapeake Bay Reflections on a population decline, Trans. Am. Fish. Soc., 119, 757–778, 1990. Craig, J. K., Crowder, L. B., and Henwood, T. A.: Spatial distribution of brown shrimp (<i>Farfantepenaeus aztecus</i>) on the northwestern Gulf of Mexico shelf Effects of abundance and hypoxia, Can. J. Fish. Aquat. Sci., 62, 1295–1308, 2005. Crema, R., Castelli, A., and Prevedelli, D.: Long term eutrophication effects on macrofaunal communities in Northern Adriatic Sea, Mar. Pollut. Bull., 22, 503–508, 1991. Dagg, M. J.: Physical and biological responses to the passage of a winter storm in the coastal and inner shelf waters of the northern Gulf of Mexico, Cont. Shelf. Res., 8, 167–178, 1988. Dauer D. M., Rodi Jr., A. J., and Ranasinghe, J. A.: Effects of low dissolved oxygen events on the macrobenthos of the lower Chesapeake Bay, Estuaries, 15, 384–391, 1992. deGroot, R. S., Wilson, M. A., and Boumans, R. M. J.: A typology for the classification, description and valuation of ecosystem functions, good and services, Ecol. Econom., 41, 393–408, 2002. Díaz, R. J.: Overview of hypoxia around the world, J. Environ. Qual., 30, 275–281, 2001. Díaz, R. J. and Breitburg, D. L.: The hypoxic environment, in: Fish Physiology, edited by: Richards, J. G., Farrell, A. P., and Brauner, C. J., Vol. 27, Academic Press, Burlington, 1–23, 2009. Díaz, R. J. and Rosenberg, R.: Marine benthic hypoxia A review of its ecological effects and the behavioural responses of benthic macrofauna, Oceanogr. Mar. Biol. Ann. Rev., 33, 245–303, 1995. Díaz, R. J. and Rosenberg, R.: Spreading dead zones and consequences for marine ecosystems, Science, 321, 926–929, 2008. Donner, S. D., Coe, M. T., Lenters, J. D., Twine, T. E., and Foley, J. A.: Modeling the impact of hydrological changes on nitrate transport in the Mississippi River basin from 1955 to 1994, Global Biogeochem. Cy., 16, 1043, https://doi.org/10.1029/2001GB001396, 2002. Dortch, Q., Rabalais, N. N., Turner, R. E., and Qureshi, N. A.: Impacts of changing Si/N ratios and phytoplankton species composition, in: Coastal Hypoxia Consequences for Living Resources and Ecosystems, edited by: Rabalais, N. N. and Turner, R. E., Coastal and Estuarine Studies 58, American Geophysical Union, Washington DC, 37–48, 2001. Eby, L. A. and Crowder, L. B.: Hypoxia-based habitat compression in the Neuse River estuary Context-dependent shifts in behavioral avoidance thresholds, Can. J. Fish. Aquat. Sci., 59, 952–965, 2002. Eilola, K., Meier, H. E. M., and Almroth, E.: On the dynamics of oxygen, phosphorus and cyanobacteria in the Baltic Sea A model study, J. Mar. Syst., 75, 163–184, 2009. Ekau, W., Auel, H., Pörtner, H.-O., and Gilbert, D.: Impacts of hypoxia on the structure and processes in the pelagic community (zooplankton, macro-invertebrates and fish), Biogeosciences Discuss., 6, 5073–5144, 2009. Elmgren, R.: Man's impact on the ecosystem of the Baltic Sea Energy flows today and at the turn of the century, Ambio, 18, 326–332, 1989. Emanuel, K., Sundararajan, R., and Williams, J.: Hurricanes and global warming, results from downscaling IPCC AR4 simulations, B. Am. Meteorol. Soc., 89, 347–364, 2008. Emeis, K.-C., Brüchert, V., Currie, B., Endler, R., Ferdelman, T., Kiessling, A., Leipe, T., Noli-Peard, K., Struck, U., and Vogt, T.: Shallow gas in shelf sediments off the Namibian coastal upwelling ecosystem, Cont. Shelf Res., 24, 627–642, 2004. Escribano, R. and Schneider, W.: The structure and functioning of the coastal upwelling system off south/central Chile, Prog. Oceanogr., 75, 343–346, 2007. Escribano, R., Daneri, G., Farías, L., Gallardo, V. A., González, A., Gutiérrez, D., Lange, C. B., Morales, C., Pizarro, O., Ulloa, O., and Braun, M.: Biological and chemical consequences of the 1997-1998 El Niño in the Chilean coastal upwelling system A synthesis, Deep-Sea Res. II, 51, 2389–2411, 2004. Fallesen, G., Andersen, F., and Larsen, B.: Life, death and revival of the hypertrophic Mariager Fjord, Denmark, J. Mar. Syst., 25, 313–321, 2000. Farías, L. and Cornejo, M.: Effect of seasonal changes in bottom water oxygenation on sediment N oxides and N<sub>2</sub>O cycling in the coastal upwelling regime off central Chile (36.5° S), Prog. Oceanogr., 75, 561–575, 2007. Fish and Wildlife Research Institute (FWRI): Offshore red tide-associated mortalities and FWRI event response, 2005. Flemer, D. A., Kruczynski, W. L., Ruth, B. F., and Bundrick, C. M.: The relative influence of hypoxia, anoxia, and associated environmental factors as determinants of macrobenthic community structure in a northern Gulf of Mexico estuary, J. Aquat. Ecosys. Stress Recov., 6, 311–328, 1999. Flindt, M. R., Kamp-Nielsen, L., Marques, J. C., Pardal, M. A., Bocci, M., Bendoricchio, G., Salomonsen, J., Nielsen, S. N., and Jorgensen, S. E.: Description of the three shallow estuaries Mondego River (Portugal), Roskilde Fjord (Denmark) and the Lagoon of Venice (Italy), Ecol. Model., 102, 17–31, 1997. Fonfonoff, P. and Millard Jr., R. C.: Algorithms for computation of fundamental properties of seawater, UNESCO Tech. Papers in Mar. Sci., 44, 53&nbsp;pp., 1983. Fonselius, S. H.: Hydrography of the Baltic deep basins III, in: Series Hydrography Report No.&nbsp;23, Fishery Board of Sweden, Gothenberg, 1–97, 1969. Frölicher, T. L., Joos, F., Plattner, G.-K., Steinacher, M., and Doney, S. C.: Natural variability and anthropogenic trends in oceanic oxygen in a coupled carbon cycle-climate model ensemble, Global Biogeochem. Cy., 23, GB1003, https://doi.org/10.1029/2008GB003316, 2009. Fuenzalida, R, Schneider, W., Graces-Vargas, J., Bravo, L., and Lange, C.: Vertical and horizontal extension of the oxygen minimum zone in the eastern South Pacific Ocean, Deep-Sea Res. II, 56, 992–1003, 2009. Gallardo, V. A.: Large benthic microbial communities in sulfide biota under Peru–Chile subsurface countercurrent, Nature, 268, 331–332, 1977. Galloway, J. N. and Cowling, E. B.: Reactive nitrogen and the world 200 years of change, Ambio, 31, 64–71, 2002. Galloway, J. N., Dentener, F. J., Capone, D. G., Boyer, E. W., Howarth, R. W., Seitzinger, S. P., Asner, G. P., Cleveland, C. C., Green, P. A., Holland, E. A., Karl, D. M., Michaels, A. F., Porter, J. H., Townsend A. R., and Vörösmarty, C. J.: Nitrogen cycles past, present, and future, Biogeochemistry, 70, 153–226, 2004. Galloway, J. N., Townsend, A. R., Erisman, J. W., Bekunda, M., Cai, Z., Freney, J. R., Martinelli, L. A., Seitzinger, S. P., and Sutton, M. A.: Transformation of the nitrogen cycle Recent trends, questions, and potential solutions, Science, 320, 889–892, 2008. Gerlach, S. A.: Oxygen conditions improve when the salinity in the Baltic Sea decreases, Mar. Pollut. Bull., 28, 413–416, 1994. Gilbert, D., Chabot, D., Archambault, P., Rondeau, B., and Hébert, S.: Appauvrissement en oxygène dans les eaux profondes du Saint-Laurent marin Causes possibles et impacts écologiques, Le Naturaliste Canadien, 131, 67–75, 2007. Gilbert, D., Sundby, B., Gobeil, C., Mucci, A., and Tremblay, G.-H.: A seventy-two year record of diminishing deep-water oxygen in the St. Lawrence estuary The northwest Atlantic connection, Limnol. Oceanogr., 50, 1654–1666, 2005. Gilbert, D., Rabalais, N. N., Diaz, R. J., and Zhang, J.: Evidence for greater oxygen decline rates in the coastal ocean than in the open ocean, Biogeosciences Discuss., 6, 9127–9160, 2009. Gillibrand, P. A., Turrell, W. R., Moore, D. C., and Adams, R. D.: Bottom water stagnation and oxygen depletion in a Scottish sea loch, Estuar. Coast. Shelf Sci., 43, 217–235, 1996. Gooday, A. J., Jorissen, F., Levin, L. A., Middelburg, J. J., Naqvi, S. W. A., Rabalais, N. N., Scranton, M., and Zhang, J.: Historical records of coastal eutrophication-induced hypoxia, Biogeosciences, 6, 1707–1745, 2009a. Gooday, A. J., Levin, L. A., Aranda da Silva, A., Bett, B., Cowie, G., Dissard, D., Gage, J., Hughes, D., Jeffreys, R., Larkin, K., Murty, S. J., Shumaker, S, Whitcraft, C., and Woulds, C.: Faunal responses to oxygen gradients on the Pakistan margin A comparison of foraminifera, macrofauna and megafauna, Deep-Sea Res. II, 56, 488–502, 2009b. Graco, M., Farías, L., Molina, V., Gutiérrez, D., and Nielsen, L. P.: Massive developments of microbial mats following phytoplankton blooms in a eutrophic bay II Implications for nitrogen cycling, Limnol. Oceanogr., 46, 821–832, 2001. Graham, J. B.: Ecological, evolutionary, and physical factors influencing aquatic animal respiration, Am. Zool., 30, 137–146, 1990. Grall, J. and Chauvaud, L.: Marine eutrophication and benthos The need for new approaches and concepts, Global Change Biol., 8, 813–830, 2002, Grantham B. A., Chan, F., Nielsen, K. J., Fox, D. S., Barth, .J. A., Huyer, A., Lubchenco, J., and Menge, B. A.: Upwelling-driven nearshore hypoxia signals ecosystem and oceanographic changes in the northeast Pacific, Nature, 429, 749–754, 2004. Gray, J. S., Wu, R. S. S., and Or, Y. Y.: Effects of hypoxia and organic enrichment on the coastal marine environment, Mar. Ecol. Prog. Ser., 238, 249–279, 2002. Greene, R. M., Lehrter, J. C., and Hagy III, J. D.: Multiple regression models for hindcasting and forecasting midsummer hypoxia in the Gulf of Mexico, Ecol. Appl., 19, 1161–1175, 2009. Greening, H. and Janicki, A.: Toward reversal of eutrophic conditions in a subtropical estuary Water quality and seagrass response to nitrogen loading reductions in Tampa Bay, Florida, USA, Environ. Manage., 38, 163–178, 2006. Grimes, C. B.: Fishery production and the Mississippi River discharge, Fisheries, 26, 17–26, 2001. Gu, H. K., Ma, X. N., Shen, W. R., Ren, G. F., Chen, Z., Diao, H. X., Li, G. J., and Zhang, L. Y.: Marine geochemistry of nitrogen near estuary of Changjiang River II Nitrite and ammonia in sea water near estuary, J. Shandong Coll. Oceanol., 12, 31–38, 1982 (in Chinese). Gu, H. K., Xiong X. X., Liu, M. X., and Li, Y.: Marine geochemistry of nitrogen near estuary of Yangtze River I Nitrate in sea water near estuary, J. Shandong Coll. Oceanol., 11, 37–46, 1981 (in Chinese). Gunter, G.: The fertile fisheries crescent, J. Mississippi Acad. Sci., 9, 286–290, 1963. Gutiérrez, D., Gallardo, V. A., Mayor, S., Neira, C., Vásquez, C., Sellanes, J., Rivas, M., Soto, A., Carrasco, F., and Baltazar, M.: Effects of dissolved oxygen and fresh organic matter on the bioturbation potential of macrofauna in sublittoral sediments off Central Chile during the 1997/1998 El Niño, Mar. Ecol. Prog. Ser., 202, 81–99, 2000. Hagy, J. D., Boynton, W. R., Keefe, C. W., and Wood, K. V.: Hypoxia in Chesapeake Bay, 1950-2001 Long-term change in relation to nutrient loading and river flow, Estuaries, 27, 634–658, 2004. Hamukuaya, H., O'Toole, M. J., and Woodhead, P. J. M.: Observations of severe hypoxia and offshore displacement of cape hake over the Namibian shelf in 1994, S. Afr. J. Marine Sci., 19, 57–59, 1998. Harper Jr., D. E., McKinney, L. D., Salzer, R. R., and Case, R. J.: The occurrence of hypoxic bottom water off the upper Texas coast and its effects on the benthic biota, Contrib. Mar. Sci., 24, 53–79, 1981. Haug, G. H., Hughen, K. A., Sigman, D. M., Peterson, L. C., and Röhl, U.: Southward migration of the intertropical convergence zone through the Holocene, Science, 293, 1304–1308, 2001. Helsinki Commission (HELCOM): The Baltic Sea Action Plan, Helsinki, Finland, 101&nbsp;pp. online available at: <a href="http://www.helcom.fi/BSAP/en{_">http://www.helcom.fi/BSAP/en{_</a>GB/intro/}, 2007. Helly, J. J. and Levin, L. A.: Global distribution of naturally occurring marine hypoxia on continental margins, Deep-Sea Res. I, 51, 1159–1168, 2004. Hennessey, T. M.: Governance and adaptive management for estuarine ecosystems The case of Chesapeake Bay, Coastal Manage., 22, 119–145, 1994. Henry, L. M., Kennedy, R., and Keegan, B. F.: An investigation of periodic hypoxia at Ardbear Salt Lake, J. Mar. Biol. Assoc. UK, 88, 1297–1307, 2008. Holland, A. F., Shaughnessy, A. T., and Hiegel, M. H.: Long-term variation in mesohaline Chesapeake Bay macrobenthos spatial and temporal patterns, Estuaries, 10, 370–378, 1987. Horton, T.: Turning the Tide Saving the Chesapeake Bay, Island Press, Washington, DC, 386&nbsp;pp., 2003. Howarth, R. W., Swaney, D. P., Butler, T. J., and Marino, R.: Climate control on eutrophication of the Hudson River estuary, Ecosystems, 3, 210–215, 2000. Hoyos, C. D., Agudelo, P. A., Webster, P. J., and Curry, J. A.: Deconvolution of the factors contributing to the increase in global hurricane intensity, Science, 312, 94–97, 2006. Humborg, C., Ittekkot, V., Cociasu, A., and Bodungen, B. v.: Effect of Danube River dam on Black Sea biogeochemistry and ecosystem structure, Nature, 386, 385–388, 1997. Intergovernmental Panel on Climate Change (IPCC): Climate Change 2007 – Impacts, Adaptation and Vulnerability. Contribution of Working Group II to the Fourth Assessment Report of the Intergovernmental Panel on Climate, Change, edited by: Parry, M. L., Canziani, O. F. Palutikof, J. P., van der, van der Linden, P. J., and Hanson, C. E., Cambridge University Press, Cambridge, UK, 976&nbsp;pp., 2007. Irigoien X., Post, J., Castel, J., Pfeiffer, K. F., and Hellmann, B.: Nycthemeral variations of the dissolved oxygen concentration in the turbidity maximum of three European estuaries Biological vs. physical processes, J. Mar. Syst., 22, 173–177, 1999. Johansson, J. O. R.: Shifts in phytoplankton, macroalgae, and seagrass with changing nitrogen loading rates to Tampa Bay, Florida, in: Proceedings Tampa Bay Area Scientific Information Symposium, edited by: Treat, S. F., BASIS4, St. Petersburg, Florida, 31–40, 2005. Johansson, J. O. R. and Lewis III, R. R.: Recent improvements of water quality and biological indicators in Hillsborough Bay, a highly impacted subdivision of Tampa Bay, Florida, USA, in: Marine Coastal Eutrophication, The response of marine transitional systems to human impact, Problems and perspectives for restoration, edited by: Vollenweider, R. W., Marchetti, R., and Viviani, R., Elsevier Press, New York, 1191–1215, 1992. Johnson, G. C. and Gruber, N.: Decadal water mass variations along 20 W in the northeastern Atlantic Ocean, Prog. Oceanogr., 73, 277–295, 2007. Jørgensen, B. B.: Seasonal oxygen depletion in the bottom waters of a Danish fjord and its effect on the benthic community, Oikos, 34, 68–76, 1980. Justić, D.: Trend in the transparency of the northern Adriatic Sea 1911–1982, Mar. Pollut. Bull., 19, 32–35, 1988. Justić, D.: A simple oxygen index for trophic state description, Mar. Pollut. Bull., 22, 201–204, 1991a. Justić, D.: Hypoxic conditions in the northern Adriatic Sea Historical development and ecological significance, in: Tyson, R. V. and Pearson, T. H. (eds.), Modern and Ancient Continental Shelf Anoxia, Geol. Soc. Spec. Publ. 58, London, The Geological Society, London, 95–105, 1991b. Justić, D., Legović, T., and Rottini-Sandrini, L.: Trends in oxygen content 1911-1984 and occurrence of benthic mortality in the northern Adriatic Sea, Estuar. Coast. Shelf Sci., 25, 435–445, 1987. Justić, D., Rabalais, N. N., and Turner, R. E.: Effects of climate change on hypoxia in coastal waters A doubled CO<sub>2</sub> scenario for the northern Gulf of Mexico, Limnol. Oceanogr., 41, 992–1003, 1996. Justić, D., Rabalais, N. N., and Turner, R. E.: Modeling the impacts of decadal changes in riverine nutrient fluxes on coastal eutrophication near the Mississippi River delta, Ecol. Model., 152, 33–46, 2002. Justić, D., Rabalais, N. N., and Turner, R. E.: Stoichiometric nutrient balance and origin of coastal eutrophication, Mar. Pollut. Bull., 30, 41–46, 1995a. Justić, D., Rabalais, N. N., Turner, R. E., and Dortch, Q.: Changes in nutrient structure of river-dominated coastal waters, stoichiometric nutrient balance and its consequences, Estuar. Coast. Shelf Sci., 40, 339–356, 1995b. Justić, D., Rabalais, N. N., and Turner, R. E.: Simulated responses of the Gulf of Mexico hypoxia to variations in climate and anthropogenic nutrient loading, J. Mar. Syst., 42, 115–126, 2003a. Justić, D., Rabalais, N. N., and Turner, R. E.: Climatic influences on riverine nitrate flux: Implications for coastal marine eutrophication and hypoxia, Estuaries, 26, 1–11, 2003b. Kamykowski, D. and Zentara, S. J.: Hypoxia in the world ocean as recorded in the historical data set, Deep-Sea Res. I, 37, 1861–1874, 1990. Karlson, K., Rosenberg, R., and Bonsdorff, E.: Temporal and spatial large-scale effects of eutrophication and oxygen deficiency on benthic fauna in Scandinavian and Baltic waters A review, Oceanogr. Mar. Biol. Ann. Rev., 40, 427–489, 2002. Karstensen, J., Stramma, L., and Visbeck, M.: Oxygen minimum zones in the eastern tropical Atlantic and Pacific Oceans, Prog. Oceanogr., 77, 331–350, 2008. Keeling, R. F. and Garcia, H. E.: The change in oceanic O<sub>2</sub> inventory associated with recent global warming, P. Natl. Acad. Sci. USA, 99, 7848–7853, 2002. Kemp, W. M., Testa, J. M., Conley, D. J., Gilbert, D., and Hagy, J. D.: Temporal responses of coastal hypoxia to nutrient loading and physical controls, Biogeosciences, 6, 2985–3008, 2009. Kemp, W. M., Sampou, P., Caffrey, J., Mayer, M., Henriksen, K., and Boynton, W.: Ammonium recycling versus denitrification in Chesapeake Bay sediments, Limnol. Oceanogr., 35, 1545–1563, 1990. Kemp, W. M., Boynton, W. R., Adolf, J. E., Boesch, D. F., Boicourt, W. C., Brush, G., Cornwell, J. C., Fisher, T. R., Glibert, P. M., Hagy, J. D., Harding, L. W., Houde, E. D., Kimmel, D. G., Miller, W. D., Newell, R. I. E., Roman, M. R., Smith, E. M., and Stevenson, J. C.: Eutrophication of Chesapeake Bay historical trends and ecological interactions, Mar. Ecol. Prog. Ser., 303, 1–29, 2005. Kerr, R.: Global warming may be homing in on Atlantic hurricanes, Science, 314, 910–911, 2006. Kerr, R. A.: Hurricanes won't go wild, according to climate models, Science, 320, p.&nbsp;999, 2008. Kiirikki, M., Lehtoranta, J., Inkala, A., Pitkänen, H., Hietanen, S., Hall, P., Tengberg, A., Koponen, J., and Sarkkula, J.: A simple sediment process description suitable for 3D-ecosystem modelling – development and testing in the Gulf of Finland, J. Mar. Syst., 61, 55–66, 2006. Kodama K., Aoki, I., and Shimizu, M.: Long-term changes in the assemblage of demersal fishes and invertebrates in relation to environmental variations in Tokyo Bay, Japan, Fish. Manag. Ecol., 9, 303–313, 2002. Konovalov, S. K. and Murray, J. W.: Variations in the chemistry of the Black Sea on a time scale of decades 1960–1995, J. Mar. Syst., 31, 217–243, 2002. Knutson, T. R., Sirutis, J. J., Garner, S. T., Held, I. M., and Tuley, R. E.: Simulation of the recent multi-decadal increase of Atlantic hurricane activity using an 18-km-grid regional model, Bull. Am. Meteorol. Soc., 88, 1549–1565, 2007. Kristiansen, S. and Hoell, E. E.: The importance of silicon for marine production, Hydrobiologia, 484, 21–31, 2002. Kump, L. R., Pavlov, A., and Arthur, M. A.: Massive release of hydrogen sulfide to the surface ocean and atmosphere during intervals of oceanic anoxia, Geology, 33, 397–400, 2005. Kurian, S., Agnihotri, R., Borole, D. V., Naqvi, S. W. A., Ferreira, A. M., and Vale, C.: Possible solar control on primary production along the Indian west coast on decadal to centennial time scales, J. Quaternary Sci., 24, 109–116, 2009. Levin, L. A.: Deep-ocean life where oxygen is scarce, Am. Scient., 90, 436–444, 2002. Levin, L. A.: Oxygen minimum zone benthos adaptation and community response to hypoxia, Oceanogr. Mar. Biol. Ann. Rev., 41, 1–45, 2003. Levin, L. A., Gage, J. D., Marti, C., and Lamont, P. A.: Macrobenthic community structure within and beneath the oxygen minimum zone, NW Arabian Sea, Deep-Sea Res. II, 47, 189–226, 2000. Levin, L. A., Ekau, W., Gooday, A. J., Jorissen, F., Middelburg, J. J., Naqvi, S. W. A., Neira, C., Rabalais, N. N., and Zhang, J.: Effects of natural and human-induced hypoxia on coastal benthos, Biogeosciences, 6, 2063–2098, 2009a. Levin, L. A., Whitcraft, C., Mendoza, G. F., Gonzalez, J., and Cowie, G.: Oxygen and organic matter thresholds for benthic faunal activity on the Pakistan Margin oxygen minimum zone (700–1100 m), Deep-Sea Res. II, 56, 449–471, 2009b. Li, D. and Daler, D.: Ocean pollution from land-based sources East China Sea, China, Ambio, 33, 107–113, 2004. Li, D., Zhang, J., Huang, D., Wu, Y., and Liang, J.: Oxygen depletion off the Changjiang (Yangtze River) Estuary, Science in China Series D-Earth Sciences, 45, 1137–1146, 2002. Lim, H.-S., Diaz, R. J., Hong, J.-S., and Schaffner, L. C.: Hypoxia and benthic community recovery in Korean coastal waters, Mar. Pollut. Bull., 52, 1517–1526, 2006. Liu, K.-K., Atkinson, L., Quiñones, R., and Talaue-McManus, L. (eds.): Carbon and Nutrient Fluxes in Continental Margins A Global Synthesis. IGBP Book Series, Springer, Heidelberg, Germany, 744&nbsp;pp., 2010. Liu, K.-K., Seitzinger, S., Mayorga, E., Harrison, J., and Ittekkot, V.: Fluxes of nutrients and selected organic pollutants carried by rivers, in: Watersheds, Bays and Bounded Seas: The Science and Management of Semi-Enclosed Marine Systems, edited by: Urban, E. R., Sundby, B., Malanotte-Rizzoli, P., and Melillo, J. M., SCOPE 70, Island Press, Washington, DC, 141–167, 2008. Liu, S. M., Zhang, J., Chen, H. T., Wu, Y., Xiong, H., and Zhang, Z. F.: Nutrients in the Changjiang and its tributaries, Biogeochemistry, 62, 1–18, 2003. Lohrenz, S. E., Fahnenstiel, G. L., Redalje, D. G., Lang, G. A., Chen, X., and Dagg, M. J.: Variations in primary production of northern Gulf of Mexico continental shelf waters linked to nutrient inputs from the Mississippi River, Mar. Ecol. Prog. Ser., 155, 435–454, 1997. Madrid, V. M., Taylor, G. T., Scranton, M. I., and Chistoserdov, A. Y.: Phylogenetic diversity of bacterial and archaeal communities in the anoxic zone of the Cariaco Basin, Appl. Environ. Microbiol. 67, 1663–1674, 2001. Mann, M. E. and Emanuel, K. A.: Atlantic hurricane trends linked to climate change, Eos, Trans. Amer. Geophy. Union, 87, p.&nbsp;233 and p.&nbsp;244, 2006. Matear, R. J., Hirst, A. C., and McNeil, B. I.: Changes in dissolved oxygen in the Southern Ocean with climate change, Geochem. Geophys. Geosyst., 1, 2000GC000086, 2000. McGregor, H. V., Dima, M., Fischer, H. W., and Mulitza, S.: Rapid 20th-century increase in coastal upwelling off Northwest Africa, Science, 315, 637–639, 2007. McQuatters-Gollop, A., Mee, L. D., Raitsos, D. E., and Shapiro, G. I.: Non-linearities, regime shifts and recovery: the recent influence of climate on Black Sea chlorophyll, J. Mar. Syst., 74, 649–658, 2008. Mee, L. D.: Eutrophication in the Black Sea and a basin-wide approach to its control, in: Science and Integrated Coastal Management, edited by: von Bodungen, B. and Turner, R. K., Dahlem University Press, Berlin, 71–91, 2001. Mee, L. D.: Reviving dead zones, Scient. Am., November 2006, 80–85, 2006. Mee, L. D., Friedrich, J., and Gomoiu, M. T.: Restoring the Black Sea in times of uncertainty, Oceanography, 18, 100–111, 2005. Millennium Ecosystem Assessment: Ecosystems and human well-being Synthesis, Island Press, Washington DC, 155&nbsp;pp., 2005. Meybeck, M.: Global analysis of river systems From earth system controls to anthropocene syndromes, Philos. T. Roy. Soc. London, 358, 1935–1955, 2003. Meyer-Reil, L.-A. and Köster, M.: Eutrophication of marine waters effects on benthic microbial communities, Mar. Pollut. Bull., 41, 255–263, 2000. Middelburg, J. and Levin, L. A.: Coastal hypoxia and sediment biogeochemistry, Biogeosciences, 6, 1273–1293, 2009. Milliman, J. D. and Meade, R. H.: World-wide delivery of sediments to the ocean, J. Geol., 91, 1–21, 1983. Milliman, J. D., Farnsworth, K. L., Jones, P. D., Xu, K. H., and Smith, L. C.: Climatic and anthropogenic factors affecting river discharge to the global ocean, 1951–2000, Global Planet. Change, 62, 187–194, 2008. Minami, H., Kano, Y., and Ocawa, K.: Long-term variations of potential temperature and dissolved oxygen of the Japan Sea proper water, J. Oceanogr., 55, 197–205, 1999. Mirza, F. B. and Gray, J. S.: The fauna of benthic sediments from the organically enriched Oslofjord, Norway, J. Exper. Mar. Biol. Ecol., 54, 181–207, 1981. Mississippi River/Gulf of Mexico Watershed Nutrient Task Force: Action Plan for Reducing, Mitigating, and Controlling Hypoxia in the Northern Gulf of Mexico, Office of Wetlands, Oceans, and Watersheds, US Environmental Protection Agency, Washington DC, 2001. Mississippi River/Gulf of Mexico Watershed Nutrient Task Force: Gulf Hypoxia Action Plan, Office of Wetlands, Oceans, and Watersheds, US Environmental Protection Agency, Washington, DC, 2008. Monteiro, P., van der Plas, A., Melice, J.-L., and Florenchie, P.: Interannual hypoxia variability in a coastal upwelling system Ocean-shelf exchange, climate and ecosystem-state implications, Deep-Sea Res. I, 55, 435–450, 2008. Müller-Karger, F. E., Varela, R., Thunell, R., Scranton, M., Bohrer, R., Taylor, G., Capelo, J., Astor, Y., Tappa, E., Ho, T. Y., and Walsh, J. J.: Annual cycle of primary production in the Cariaco Basin Response to upwelling and implications for vertical export, J. Geophys. Res., 106, 4527–4542, 2001. Müller-Karger, F. E., Varela, R., Thunell, R., Astor, Y., Zhang, H., Luerssen, R., and Hu, C.: Processes of coastal upwelling and carbon flux in the Cariaco Basin, Deep-Sea Res. II, 51, 927–943, 2004. Nakata, K., Sugioka, S.-I., and Hosaka T.: Hindcast of a Japan Sea oil spill, Spill Sci. Technol. Bull., 4, 219–229, 1997. Naqvi, S. W. A., Jayakumar, D. A., Narvekar, P. V., Naik, H., Sarma, V. V. S. S., D'Souza, W., Joseph, S., and George, M. D.: Increased marine production of N<sub>2</sub>O due to intensifying anoxia on the Indian continental shelf, Nature, 408, 346–349, 2000. Naqvi, S. W., Naik, H., Jayakumar, D. A., Shailaja, M. S., and Narvekar, P. V.: Seasonal oxygen deficiency over the western continental shelf of India, in: Past and Present Water Column Anoxia, edited by: Neretin, L. N., Dordrecht, The Netherlands, 195–224, 2006a. Naqvi, S. W. A., Naik, H., Pratihary, A., D'Souza, W., Narvekar, P. V., Jayakumar, D. A., Devol, A. H., Yoshinari, T., and Saino, T.: Coastal versus open-ocean denitrification in the Arabian Sea, Biogeosciences, 3, 621–633, 2006b. National Research Council (NRC): Clean Coastal Waters – Understanding and Reducing the Effects of Nutrient Pollution, National Academy Press, Washington, DC, 2000. National Research Council (NRC): The Mississippi River and the Clean Water Act: progress, challenges, and opportunities, National Academy Press, Washington, DC, 2008. Nehring, D.: Eutrophication of the Baltic Sea, Sci. Total Environ. Suppl., 1992, 673–682, 1992. Neretin, L. N.: Past and Present Water Column Anoxia. IV. Earth and Environmental Sciences, Vol. 64, NATO Science Series, Springer, 541&nbsp;pp., 2006. Newcombe, C. L. and Horne, W. A.: Oxygen-poor waters of the Chesapeake Bay, Science, 88, 80–81, 1938. Nissling, A. and Vallin, L.: The ability of Baltic cod eggs to maintain neutral buoyancy and the opportunity for survival in fluctuating conditions in the Baltic Sea, J. Fish Biol., 48, 217–227, 1996. Nixon, S. W.: Coastal marine eutrophication A definition, social causes, and future concerns, Ophelia, 41, 199–219, 1995. Nixon, S. W.: Replacing the Nile Are anthropogenic nutrients providing the fertility once brought to the Mediterranean by a great river?, Ambio, 32, 30–39, 2003. Nixon, S. W.: The artificial Nile, Am. Sci., 94, 158–165, 2004. Nixon, S. W.: Eutophication and the macroscope, Hydrobiologia, 629, 5–19, 2009. Nixon, S. W. and Buckley, B. A.: "A strikingly rich zone" Nutrient enrichment and secondary production in coastal marine ecosystems, Estuaries, 25, 782–796, 2002. Nizzoli, D., Bartoli, M., Cooper, M., Welsh, D. T., Underwood, G. J. C., and Viaroli, P.: Implications for oxygen, nutrient fluxes and denitrification rates during the early stage of sediment colonisation by the polychaete <i>Nereis</i> spp. in four estuaries, Estuar. Coast. Shelf Sci., 75, 125–134, 2007. Oczkowskia, A. J., Nixon, S. W., Grangera, S. L., El-Sayed, A.-F. M., and McKinney, R. A.: Anthropogenic enhancement of Egypt's Mediterranean fishery, P. Natl. Acad. Sci. USA., 106, 1364–1367, 2009. Officer, C. B. and Ryther, J. H.: The possible importance of silicon in marine eutrophication, Mar. Ecol. Prog. Ser., 3, 83–91, 1980. Oguz, T.: Long-term impacts of anthropogenic forcing on the Black Sea ecosystem, Oceanography, 18, 104–113, 2005. Osterman, L. E., Poore, R. Z., Swarzenski, P. W., and Turner, R. E.: Reconstructing a 180 yr record of natural and anthropogenic induced low-oxygen conditions from Louisiana continental shelf sediments, Geology, 33, 329–332, 2005. Osterman, L. E., Poore, R. Z., Swarzenski, P. W., Senn, D. R., and DiMarco, S. F.: The 20th-century development and expansion of Louisiana shelf hypoxia, Gulf of Mexico, Geo-Mar. Lett., 29, 405–414, 2009. Ostrom, N. E., Carrick, H. J., and Twiss, M. R.: Evaluation of primary production in Lake Erie by multiple proxies, Oecologia, 144, 115–124, Erratum 145, p.&nbsp;669, 2005. O'Toole, M. J., Shannon, V., de Barros Neto, V., and Malan, D.: Integrated management of the Benguela Current region A framework for future development, in: Science and Integrated Coastal Management, edited by: von Bodungen, B. and Turner, R. K., Dahlem University Press, 229–251, 2001. Paerl, H. W., Bales, J. D., Ausley, L. W., Buzzelli, C. P., Crowder, L. B., Eby, L. A., Go, M., Peierls, B. L., Richardson, T. L., and Ramus, J. S.: Hurricane's hydrological, ecological effects linger in major US estuary, Eos, Trans. Am. Geophys. Union, 81, p.&nbsp;457 and p.&nbsp;462, 2000. Panchang, R., Nigam, R., Linshy, V., Rana, S. S., and Ingole, B. S.: Effect of oxygen manipulations on benthic foraminifera A preliminary experiment, Indian J. Mar. Sci., 35, 235–239, 2006. Parker-Stetter. S. L. and Horne J. K.: Nekton distribution and midwater hypoxia A seasonal, diel prey refuge?, Estuar. Coast. Shelf Sci., 81, 13–18, 2008. Paulmier, A. and Ruiz-Pino, D.: Oxygen minimum zones (OMZs) in the modern ocean, Prog. Oceanogr., 80, 113–128, 2009. Pauly, D. and Christensen, V.: Primary production required to sustain global fisheries, Nature, 374, 255–257, 1995. Pearce, C. R., Cohen, A. S., Coe, A. L., and Burton, K. W.: Molybdenum isotope evidence for global ocean anoxia coupled with perturbations to the carbon cycle during the Early Jurassic, Geology, 36, 231–234, 2008. Pearson, T. H., Josefson, A. B., and Rosenberg, R.: Petersen's benthic stations revisited I Is the Kattcgatt becoming eutrophic?, J. Exp. Mar. Biol. Ecol., 92, 157–206, 1985. Petersen, C. G. J.: Valuation of the sea I, Rep. Danish Biol. Stat. No. 30, January-76, 1911. Pizarro, O., Shaffer, G., Dewitte, B., and Ramos, M.: Dynamics of seasonal and interannual variability of the Peru-Chile undercurrent, Geophys. Res. Lett., 29, 22-1–22-4, 2002. Pörtner, H. O. and Knust, R.: Climate change affects marine fishes through the oxygen limitation of thermal tolerance, Science, 315, 95–97, 2007. Prince, E. D. and Goodyear, C. P.: Hypoxia-based habitat compression of tropical pelagic fishes, Fish. Oceanogr., 15, 451–464, 2006. Qu, J. G., Xu, Z. L., Long, Q., Wang, L., Shen, X. M., Zhang, J., and Cai, Y. L.: East China Sea, UNEP/GIWA Regional Assessment 36. University of Kalmar, Sweden, 96&nbsp;pp., 2005. Quiñones-Rivera, Z. J., Wissel, B., Justić, D., and Fry, B.: Partitioning oxygen sources and sinks in a stratified, eutrophic coastal ecosystem using stable oxygen isotopes, Mar. Ecol. Prog. Ser., 342, 60–83, 2007. Quiñones-Rivera, Z. J., Wissel, B., Rabalais, N. N., and Justić, D.: Effects of biological and physical factors on seasonal oxygen dynamics in a stratified, eutrophic coastal ecosystem, Limnol. Oceanogr., 55, 289–304, 2010. Rabalais, N. N.: Eutrophication, in: The Global Coastal Ocean Multiscale Interdisciplinary Processes, edited by: Robinson, A. R., McCarthy, J., and Rothschild, B. J., The Sea, Vol. 13, Harvard University Press, 819–865, 2004. Rabalais, N. N. and Gilbert, D.: Distribution and consequences of hypoxia, in: Watersheds, Bays, and Bounded Seas The Science and Management of Semi-Enclosed Marine Systems, edited by: Urban, E. R., Sundby, B., Malanotte-Rizzoli, P., and Milello, J., Island Press, Washington DC, 209–225, 2008. Rabalais, N. N. and Turner, R. E. (eds.): Coastal Hypoxia Consequences for Living Resources and Ecosystems, Coastal and Estuarine Studies 58, American Geophysical Union, Washington DC, 454&nbsp;pp., 2001. Rabalais, N. N. and Turner, R. E.: Oxygen depletion in the Gulf of Mexico adjacent to the Mississippi River, in: Past and Present Marine Water Column Anoxia, edited by: Neretin, L. N., NATO Science Series IV-Earth and Environmental Sciences, Kluwer, 225–245, 2006. Rabalais, N. N., Harper Jr., D. E., and Turner, R. E.: Responses of nekton and demersal and benthic fauna to decreasing oxygen concentrations, in: Coastal Hypoxia Consequences for Living Resources and Ecosystems, edited by: Rabalais, N. N. and Turner, R. E., Coastal and Estuarine Studies 58, American Geophysical Union, Washington, DC, 115–128, 2001a. Rabalais, N. N., Smith, L. E., Harper Jr., D. E., and Justić, D.: Effects of seasonal hypoxia on continental shelf benthos, in: Coastal Hypoxia Consequences for Living Resources and Ecosystems, edited by: Rabalais, N. N. and Turner, R. E., Coastal and Estuarine Studies 58, American Geophysical Union, Washington, DC, 211–240, 2001b. Rabalais, N. N., Turner, R. E., Díaz, R. J., and Justić, D.: Global change and eutrophication of coastal waters, ICES J. Mar. Sci., 66, 1528–1537, 2009. Rabalais, N. N., Turner, R. E., Justić, D., Dortch, Q., Wiseman Jr., W. J., and Sen Gupta, B. K.: Nutrient changes in the Mississippi River and system responses on the adjacent continental shelf, Estuaries, 19, 386–407, 1996. Rabalais, N. N., Turner, R. E., Sen Gupta, B. K., Boesch, D. F., Chapman, P., and Murrell, M. C.: Characterization and long-term trends of hypoxia in the northern Gulf of Mexico Does the science support the Action Plan?, Estuar. Coasts, 30, 753–772, 2007a. Rabalais, N. N., Turner, R. E., Sen Gupta, B. K., Platon, E., and Parsons, M. L.: Sediments tell the history of eutrophication and hypoxia in the northern Gulf of Mexico, Ecol. Applic. Spec. Issue Nutrient Enrichment of Estuarine and Coastal Marine Environments, 17 Supplement, S129–S143, 2007b. Rabalais, N. N., Turner, R. E., Wiseman Jr., W. J.,, and Boesch, D. F.: A brief summary of hypoxia on the northern Gulf of Mexico continental shelf 1985-1988, in: Modern and Ancient Continental Shelf Anoxia, edited by: Tyson, R. V. and Pearson, T. H., Geological Society Special Publication No. 58, The Geological Society, London, 35–47, 1991. Rabalais, N. N., Turner, R. E., Wiseman Jr., W. J., and Dortch, Q.: Consequences of the 1993 Mississippi River flood in the Gulf of Mexico, Regulated Rivers Res. Manag., 14, 161–177, 1998. Rao, C. K., Naqvi, S. W. A., Kumar, M. D., Varaprasad, S. J. D., Jayakumar, D. A., George, M. D., and Singbal, S. Y. S.: Hydrochemistry of the Bay of Bengal Possible reasons for a different water column cycling of carbon and nitrogen from the Arabian Sea, Mar. Chem., 47, 279–290, 1994. Renaud, M.: Hypoxia in Louisiana coastal waters during 1983 Implications for fisheries, Fish. Bull., 84, 19–26, 1986. Richards, F. A.: Oxygen in the ocean, in: Treatise on Marine Ecology and Paleoecology, edited by: Hedgpeth, J. W., Vol. 1, Waverly Press, Baltimore, Maryland, 185–238, 1957. Richards, F. A.: Anoxic basins and fjords, edited by: Riley, J. P. and Skirrow, G., Chem. Oceanogr., Vol. 1, Academic Press, New York, 611–645, 1965. Riebesell, U., Schulz, K., Bellerby, R., Botros, M., Fritsche, P., Meyerhofer, M., Neill, C., Nondal, G., Oschlies, A., Wohlers, J., and Zollner, E.: Enhanced biological carbon consumption in a high CO<sub>2</sub> ocean, Nature, 450, 545–548, 2007. Riedel, B., Zuschin, M., and Stachowitsch, M.: Dead zones: a future worst-case scenario for northern Adriatic biodiversity, in: Climate warming and related changes in Mediterranean marine biota, edited by: Briand, F., No. 35, CIESM Workshop Monographs, Monaco, 73–78, 2008. Ritter, C. and Montagna, P. A.: Seasonal hypoxia and models of benthic response in a Texas bay, Estuaries, 22, 7–20, 1999. Robbins, B. D.: Quantifying temporal change in seagrass areal coverage The use of GIS and low resolution aerial photography, Aquat. Bot., 58, 259–267, 1997. Rosenberg, R.: Effects of oxygen deficiency on benthic macrofauna in fjords, edited by: Freeland, H. J., Farmer, D. M., and Levings, C. D., Fjord Oceanography, Plenum Publishing Corp., New York, 499–514, 1980. Rosenberg, R. and Diaz, R. J.: Sulfur bacteria (<i>Beggiatoa</i> spp.) mats indicate hypoxic conditions in the inner Stockholm Archipelago, Ambio, 22, 32–36, 1993. Rosenberg, R. and Loo, L. O.: Marine eutrophication induced oxygen deficiency effects on soft bottom fauna, western Sweden, Ophelia, 29, 213–225, 1988. Rumohr, H., Bonsdorff, E., and Pearson, T. H.: Zoobenthic succession in Baltic sedimentary habitats, Arch. Fish. Mar. Res., 44, 170–214, 1996. Ryther, J. H.: Photosynthesis and fish production in the sea, Science, 166, 72–76, 1996. Sakko, A. L.: The influence of the Benguela upwelling system on Namibia's marine biodiversity, Biodiv. Conserv., 7, 419–433, 1998. Savage, C., Elmgren, R., and Larsson, U.: Effects of sewage-derived nutrients on an estuarine macrobenthic community, Mar. Ecol. Prog. Ser., 243, 67–82, 2002. Savrda, C. E., Bottjer, D. J., and Gorsline, D. S.: Development of a comprehensive oxygen-deficient marine biofacies model Evidence from Santa Monica, San Pedro, and Santa Barbara Basins, California Continental Borderland, Amer. Assoc. Petrol. Geol. Bull., 68, 1179–1192, 1984. Scavia, D., Rabalais, N. N., Turner, R. E., Justić, D., and Wiseman Jr., W. J.: Predicting the response of Gulf of Mexico hypoxia to variations in Mississippi River nitrogen load, Limnol. Oceanogr., 48, 951–956, 2003. Schramm, W.: Factors influencing seaweed responses to eutrophication Some results from EU-project EUMAC, J. Appl. Phycol., 11, 69–78, 1999. Scully, M. E., Friedrichs, C., and Brubaker, J.: Control of estuarine stratification and mixing by wind-induced straining of the estuarine density field, Estuaries, 28, 321–326, 2005. Scully, M. E.: The importance of decadal-scale climate variability to wind-driven modulation of hypoxia in Chesapeake Bay, Nature Precedings, online available at: <a href="http://hdl.handle.net/10101/npre.2009.3308.1">http://hdl.handle.net/10101/npre.2009.3308.1</a>, 2009. Secor, D. H. and Gunderson, T. E.: Effects of hypoxia and temperature on survival, growth, and respiration of juvenile Atlantic sturgeon, <i>Acipenser oxyrinchus</i>, Fish. Bull., 96, 603–613, 1998. Secor, D. H. and Niklitschek, E. J.: Hypoxia and Sturgeons, Report to the Chesapeake Bay Program Dissolved Oxygen Criteria Team, Chesapeake Biological Laboratory, University of Maryland Center for Environmental Science, Solomons, Maryland, 26&nbsp;pp., 2001. Seitzinger, S. P., Kroeze, C., Bouwman, A. F., Caraco, N., Dentene, F., and Styles, R. V.: Global patterns of dissolved inorganic and particulate nitrogen inputs to coastal systems Recent conditions and future projections, Estuaries, 25, 640–655, 2002. Sen Gupta, B. K., Turner, R. E., and Rabalais, N. N.: Seasonal oxygen depletion in continental-shelf waters of Louisiana Historical record of benthic foraminifers, Geology, 24, 227–230, 1996. Shaffer, G., Olsen, S. M., and Pedersen, J. O. P.: Long-term oxygen depletion in response to carbon dioxide emissions from fossil fuels, Nature Geoscience, 2, 105–109, https://doi.org/10.1028/NGEO420, 2009. Sherwood, E. T.: Tampa Bay water quality assessment, Tampa Bay Estuary Program Tech. Rpt. {#}01-09, Tampa Bay Estuary Program, St. Petersburg, Florida, 2009. Simon, J. L.: Tampa Bay estuarine system A synopsis, Florida Sci., 37, 217–244, 1974. Simpson, T. W., Sharpley, A., Howarth, R. W., Paerl, H. W., and Mankin, K.: The new gold rush Fueling ethanol production while protecting water quality, J. Environ. Qual., 37, 318–324, 2008. Skei, J. M.: Permanently anoxic marine basins Exchange of substances across boundaries, Ecol. Bull., 35, 419–429, 1983. Snelgrove, P. V. R., Flitner, M., Urban, E. R., Jr., Ekau, W., Glaser, M., Lotze, H. K., Phillipart, K., Sompongchaiyakul, P., Yuwono, E., Melillo, J., Meybek, M., Rabalais, N. and Zhang, J.: Governance and management of ecosystem services, in: Watersheds, Bays, and Bounded Seas The Science and Management of Semi-Enclosed Marine Systems, edited by: Urban, E. R., Sundby, B., Malanotte-Rizzoli, P., and Milello, J., Island Press, Washington, DC, 49–76, 2008. Stachowitsch, M.: Mass mortality in the Gulf of Trieste The course of community destruction, Mar. Ecol., 5, 243–264, 1984. Stachowitsch, M.: Anoxia in the Northern Adriatic Sea Rapid death, slow recovery, in: Modern and Ancient Continental Shelf Anoxia, edited by: Tyson, R. V. and Pearson, T. H., Geol. Soc. Spec. Publ. No. 58, The Geological Society, London, 119–129, 1991. Stoeck, T., Taylor, G. T., and Epstein, S. S.: Novel eukaryotes from the permanently anoxic Cariaco Basin (Caribbean Sea), Appl. Environ. Microbiol., 69, 5656–5663, 2003. Stramma, L., Johnson, G. C., Sprintall, J., and Mohrholz, V.: Expanding oxygen-minimum zones in the tropical oceans, Science, 320, 655–658, 2008. Swanson, R. L. and Sindermann, C. J. (eds.): Oxygen Depletion and Associated Benthic Mortalities in New York Bight, 1976, NOAA Professional Paper 11, US Department of Commerce National Oceanic and Atmospheric Administration, US Government Printing Office, Washington, DC, 345&nbsp;pp., 1979. Tampa Bay Estuary Program (TBEP): Charting the course, the comprehensive conservation and management plan for Tampa Bay, online available at: <a href="http//www.tbep.org/">http//www.tbep.org/</a>, 2006. Taylor, G. T., Scranton, M. I., Iabichella, M., Ho, T.-Y., Thunell, R. C., and Varela, R.: Chemoautotrophy in the redox transition zone of the Cariaco Basin A significant source of midwater organic carbon production, Limnol. Oceanogr., 46, 148–163, 2001. Thibodeau, B., de Vernal, A., and Mucci, A.: Recent eutrophication and consequent hypoxia in the bottom water of the Lower St. Lawrence Estuary Micropaleontological and geochemical evidence, Mar. Geol., 231, 37–50, 2006. Thomas, H.: Remineralization ratios of carbon, nutrients, and oxygen in the North Atlantic Ocean A field data-based assessment, Global Biogeochem. Cy., 16, 24-1–24-12, 2002. Tilman, D., Kilham, S. S., and Kilham, P.: Phytoplankton community ecology The role of limiting nutrients, Ann. Rev. Ecol. Syst., 13, 349–372, 1982. Tilman, D., Fargione, J., Wolff, B., D'Antonio, C., Dobson, A., Howarth, R., Schindler, D., Schlesinger, W. H., Simberloff, D., and Swackhamer, D.: Forecasting agriculturally driven global environmental change, Science, 292, 281–284, 2001. Tolmazin, R.: Changing coastal oceanography of the Black Sea I Northwestern shelf, Prog. Oceanogr., 15, 217–276, 1985. Tomasko, D. A., Anastasiou, C., and Kovach, C.: Dissolved oxygen dynamics in Charlotte Harbor and its contributing watershed, in response to hurricanes Charley, Frances, and Jeanne Impacts and recovery, Estuar. Coasts, 29, 932–938, 2006. Tong, L. and Zhang, J.: Chinese IMBER/GLOBEC program progress Dead zone survey, IMBER Update, 6, 6–8, 2007. Trenberth, K.: Uncertainty in hurricanes and global warming, Science, 308, 1753–1754, 2005. Tunnicliffe, V.: High species diversity and abundance of the epibenthic community in an oxygen-deficient basin, Nature, 294, 354–356, 1981. Turner, R. E.: The effects of eutrophication on pelagic and demersal marine food webs, in: Coastal Hypoxia Consequences for Living Resources and Ecosystems, edited by: Rabalais, N. N. and Turner, R. E., Coastal and Estuarine Studies 58, American Geophysical Union, Washington, DC, 371–398, 2001. Turner, R. E. and Rabalais, N. N.: Coastal eutrophication near the Mississippi river delta, Nature, 368, 619–621, 1994. Turner, R. E., Qureshi, N., Rabalais, N. N., Dortch, Q., Justić, D., Shaw, R. F., and Cope, J.: Fluctuating silicate:nitrate ratios and coastal plankton food webs, P. Natl. Acad. Sci. USA, 95, 13048–13051, 1998. Turner, R. E., Rabalais, N. N., and Justić, D.: Gulf of Mexico hypoxia Alternate states and a legacy, Environ. Sci. Technol., 42, 2323–2327, 2008. Turner, R. E., Rabalais, N. N., and Justić, D.: Predicting summer hypoxia in the northern Gulf of Mexico Riverine N, P, and Si loading, Mar. Pollut. Bull., 52, 139–148, 2006. Turner, R. E., Rabalais, N. N., Justić, D., and Dortch, Q.: Global patterns of dissolved silicate and nitrogen in large rivers, Biogeochemistry, 64, 297–317, 2003. Tyler, R. M., Brady, D. C., and Targett, T. E.: Temporal and spatial dynamics of diel-cycling hypoxia in estuarine tributaries, Estuar. Coasts, 32, 123–145, 2009. Tyson, R. V. and Pearson, T. H. (eds.): Modern and Ancient Continental Shelf Anoxia, Geol. Soc. Spec. Publ. No. 58, The Geological Society, London, 490&nbsp;pp., 1991a. Tyson, R. V. and Pearson, T. H.: Modern and ancient continental shelf anoxia An overview, in: Modern and Ancient Continental Shelf Anoxia, edited by: Tyson, R. V. and Pearson, T. H., Geol. Soc. Spec. Publ. No. 58, The Geological Society, London, 1–24, 1991b. US Environmental Protection Agency (USEPA): Hypoxia in the Northern Gulf of Mexico An Update. Science Advisory Board, Hypoxia Assessment Panel, EPA-SAB-08-004, 333&nbsp;pp., 2008. Ueda, N., Tsutsumi, H., Yamada, M., Hanamoto, K., and Montani, S.: Impacts of oxygen-deficient water on the macrobenthic fauna of Dokai Bay and on adjacent intertidal flats, in Kitakyushu, Japan, Mar. Pollut. Bull., 40, 906–913, 2000. Vahtera, E., Conley, D. J., Gustafsson, B. G., Kuosa, H., Pitkänen, H., Savchuk, O. P., Tamminen, T., Viitasalo, M., Voss, M., Wasmund, N., and Wulff, F.: Internal ecosystem feedbacks enhance nitrogen fixing cyanobacteria blooms and complicate management in the Baltic Sea, Ambio, 36, 186–194, 2007. Vaquer-Sunyer, R. and Duarte, C. M.: Thresholds of hypoxia for marine biodiversity, P. Natl. Acad. Sci. USA, 105, 15452–15457, 2008. Vecchi, G. A. and Soden, B. J.: Global warming and the weakening of the tropical circulation, J. Climate, 20, 4316–4340, 2007. Verity, P. G., Alber, M., and Bricker, S. B.: Development of hypoxia in well-mixed subtropical estuaries in the southeastern USA, Estuar. Coasts, 29, 665–673, 2006. Walsh, J. J.: Importance of continental margins in the marine biogeochemical cycling of carbon and nitrogen, Nature, 350, 53–55, 1991. Wang, B.: Cultural eutrophication in the Changjiang (Yangtze River) plume History and perspective, Estuar. Coast. Shelf Sci., 69, 471–477, 2006. Wang, H., Yang, Z., Saito, Y., Liu, J. P., and Sun, X.: Interannual and seasonal variation of the Huanghe (Yellow River) water discharge over the past 50 years Connections to impacts from ENSO events and dams, Global Planet. Change, 50, 212–225, 2006. Wang, X., Depew, D., Schiff, S., and Smith, R. E. H.: Photosynthesis, respiration, and stable isotopes of oxygen in a large oligotrophic lake (Lake Erie, U.S.A.-Canada), Can. J. Fish. Aquat. Sci., 65, 2320–2331, 2008. Wang, L. and Justić, D.: A modeling study of the physical processes affecting the development of seasonal hypoxia over the inner Louisiana-Texas shelf Circulation and stratification, Cont. Shelf Res., 29, 1464–1476, 2006. Ward, C. H., Bender, M. E., and Reish, D. J. (eds.): The offshore ecology investigation Effects of oil drilling and production in a coastal environment, Rice University Studies, 65, 1–589, 1979. Weeks, S., Currie, B., and Bakun, A.: Massive emission of toxic gas in the Atlantic, Nature, 415, 493–494, 2002. Wei, H., He, Y., Li, Q., Liu, Z., and Wang, H.: Summer hypoxia adjacent to the Changjiang Estuary, J. Mar. Syst., 67, 292–303, 2007. Weissberger, E. J., Coiro, L. L., and Davey, E. W.: Effects of hypoxia on animal burrow construction and consequent effects on sediment redox profiles, J. Exp. Mar. Biol. Ecol., 371, 60–67, 2009. Whitledge, T. E.: Nationwide review of oxygen depletion and eutrophication in estuarine and coastal waters Executive summary, Report to National Ocean Service, National Oceanic and Atmospheric Administration. Brookhaven National Laboratory, Upton, New York, 28&nbsp;pp., 1985. Whitney, F. A., Freeland, H. J., and Robert, M.: Persistently declining oxygen levels in the interior waters of the eastern subarctic Pacific, Prog. Oceanogr., 75, 179–199, 2007. Wilson, P. A. and Norris, R. D.: Warm tropical ocean surface and global anoxia during the mid-Cretaceous period, Nature, 412, 425–429, 2001. Wolock, D. M. and McCabe, G. J.: Estimates of runoff using water-balance and atmospheric general circulation models, J. Am. Water Resour. Assoc., 35, 1341–1350, 1999. Wu, R. S. S.: Hypoxia: from molecular responses to ecosystem responses, Mar. Pollut. Bull., 45, 35–45, 2002. Wu, R. S. S., Zhou, B. S., Randall, D. J., Woo, N. Y. S., and Lam, P. K. S.: Aquatic hypoxia is an endocrine disruptor and impairs fish reproduction, Environ. Sci. Technol., 37, 1137–1141, 2003. Wyrtki, K.: Oceanography of the eastern equatorial Pacific Ocean, Oceanogr. Mar. Biol. Ann. Rev., 4, 33–68, 1966. Yang, S., Li, C., and Cai, J.: Geochemical compositions of core sediments in eastern China Implication for Late Cenozoic palaeoenvironmental changes, Palaeogeo. Palaeoclimat. Palaeoecol., 229, 287–302, 2006. Zaitsev, Y. P.: Recent changes in the trophic structure of the Black Sea, Fish. Oceanogr., 1, 180–189, 1992. Zhang, J., Huang, W. W., Liu, M. G., and Cui, J. Z.: Ecosocial impact and chemical regimes of large Chinese rivers A short discussion, Water Res., 28, 609–617, 1994. Zhang, J., Zhang, Z. F., Liu, S. M., Wu, Y., Xiong, H., and Chen, H. T.: Human impacts on the large world rivers Would the Changjiang (Yangtze River) be an illustration?, Global Biogeochem. Cy., 13, 1099–1105, 1999. Zhu, Z. Y.: Hypoxia in the Changjiang Estuary and its adjacent area – Started with phytoplankton pigments, Ph.D. Dissertation, East China Normal University, Shanghai, 209&nbsp;pp., 2007 (in Chinese). Zillén, L., Conley, D. J., Andrén, T., Andrén, E., and Björck, S.: Past occurrences of hypoxia in the Baltic Sea and the role of climate variability, environmental change and human impact, Earth Sci. Rev., 91, 77–92, 2008.