Tropical forests are highly threatened by the expansion of the agricultural frontier, use of fire and subsequent deforestation. NW Amazonia is the wettest part of the basin and the role of fire is still largely unknown in this subregion. In this study, we compared fire regimes in five countries sharing this tropical biome (Venezuela, Colombia, Ecuador, Peru and Brazil). We studied fire activity in relation to proximity to roads and rivers and how fire occurs in relation to forest fragmentation.