This publication provides a comprehensive review of the use of GDGTs (Glycerol Dialkyl Glycerol Tetraethers) for reconstructing past temperatures, with a particular focus on marine applications. It covers the full research workflow — from sample collection and processing to analytical methodologies, data interpretation, and data archiving. Importantly, the authors highlight best practices and propose recommendations to standardize approaches across the field. This review therefore serves as a valuable reference for both the paleoclimatology and organic geochemistry communities.