Inland saline lakes are crucial in the global carbon cycle, but increased droughts may alter their carbon exchange capacity. We measured CO₂ and CH₄ fluxes in a Mediterranean saline lake using the eddy covariance method under dry and wet conditions. We found the lake acts as a carbon sink during wet periods but not during droughts. These results highlight the importance of saline lakes in carbon sequestration and their vulnerability to climate-change-induced droughts.